Alzheimer
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Global dementia cases forecasted to triple by 2050: New analysis shows a decrease in prevalence due to education countered by increase due to heart health risk factors
Positive trends in global education access are expected to decrease dementia prevalence worldwide by 6.2 million cases by the year…
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Evidence of sustained benefits of pimavanserin for dementia-related psychosis
Evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis has been published. Up to…
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Gamma-secretase ‘buckles up’ to reach its destination
A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to…
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Spinal fluid biomarkers detect neurodegeneration, Alzheimer’s disease in living patients
Alzheimer’s disease and related diseases can still only be confirmed in deceased patients’ brains via autopsy. Even so, the development…
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Common antibiotic no more effective than placebo in preventing COVID-19 symptoms among non-hospitalized: Outpatient study found limited effect of azithromycin on progression of disease
A UC San Francisco study has found that the antibiotic azithromycin was no more effective than a placebo in preventing…
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Signaling molecule may help prevent Alzheimer’s disease: Interleukin-3 may reprogram immune responses in the brain that cause cell death and lead to dementia.
New research in humans and mice identifies a particular signaling molecule that can help modify inflammation and the immune system…
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Metal-based molecules show promise against the build-up of Alzheimer’s peptides
In lab tests, Imperial researchers have created a metal-based molecule that inhibits the build-up of a peptide associated with Alzheimer’s…
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Recent study identifies 11 candidate genetic variants for Alzheimer’s disease
A recently published study co-authored by University of Kentucky Sanders-Brown Center on Aging researcher Justin Miller, Ph.D., identifies 11 rare…
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Discovery of nano-sized molecules that might inhibit Alzheimer’s and Parkinson’s diseases
Nanosized molecules of a particular chemical element can inhibit the formation of plaque in the brain tissues. This new discovery…
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Success in reversing dementia in mice sets the stage for human clinical trials
Researchers have identified a new treatment candidate that appears to not only halt neurodegenerative symptoms in mouse models of dementia…
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GluN3A knockout mouse: Alternative model for Alzheimer’s neurodegeneration
In the context of recent debate over the FDA’s approval of aducanumab, it’s refreshing to learn about a model of…
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Researchers question prevailing Alzheimer’s theory with new discovery: Scientists say restoring a brain protein, not removing amyloid plaques, should be the target of Alzheimer’s dementia therapies
Experts estimate more than 6 million Americans are living with Alzheimer’s dementia. But a recent study, led by the University…
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